Prevalence of Isotretinoin Therapy in Adolescents and Young Adults With and Without Atopic Dermatitis: A Nationwide Prescription-based Population Study

Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with dermatitis are affected by severe acne tolerability lacking. The aim this study is investigate therapy in compare nationwide prevalence individuals without All Norwegian residents were followed for 17 years until age 20–22 2020. Approximately 28% had been treated acne, 8% received before 23 years. In those over old, significantly more than without. At 22 years, 2.21% (95% confidence interval 1.92–2.49) isotretinoin, compared 1.55% 1.44–1.65) without, representing 42.8% (1.43; 95% 1.24–1.65) higher use Patients who long-term treatment (probable dermatitis) tolerated similarly short-term mild dermatitis). There was topical corticosteroids during Conclusively, (isotretinoin therapy) associated at population level young adults.